Human Anti-Spike RBD (CR3022)

Recombinant human monoclonal antibody against the Receptor Binding Domain of SAR-CoV-2 Spike protein (subunit 1). Human Anti-RBD (CR3022) is produced in Nicotiana benthamiana plants for use in Western Blot and ELISA applications.

100 µg     |     Catalogue Number: CBT_A0006

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The Spike Protein is the characteristic surface antigen of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), or 2019 Novel Coronavirus. Spike protein is assembled as a trimer consisting of S1 and S2 domains. The S1 domain of SARS-CoV-2 contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2) located on target cells of human and bat hosts. Our plant-made recombinant monoclonal antibody recognizes an epitope within the coronavirus receptor binding domain (RBD) and binds a cross-reactive epitope also present in the novel coronavirus. CR3022 works well in ELISA and Western blot applications.

Additional information

Available Unit Size

0.1mg, 1mg, 10mg, 100mg, 200mg

Key Benefits

This product is a plant-made, recombinant monoclonal antibody which offers several benefits including:

  • No animals or animal products are used in its development.
  • Proteins are fused at the genetic level for increased reproducibility of results.
  • BSA and Azide free.

For more information on plant-made, recombinant monoclonal antibodies click here.

Datasheet

Product Name PtX™ Human Anti-SARS-CoV-2 Spike RBD (CR3022) Recombinant Antibody
Catalogue Number CBT_A0006
Expression Host Nicotiana benthamiana plants
Clonality Monoclonal, recombinant.
Species and Isotype CR3022 variable regions fused to human IgG1: Heavy chain CR3022 (GenBank: DQ168569.1) – Human Heavy chain IgG1 (UniProtKB/ Swiss-Prot: P01857.1); Light chain CR3022 (GenBank: DQ168570.1) – Human Kappa chain (UniProtKB/Swiss-Prot: P01834.2)
Tag Human IgG1 Fc Tag
Reporter Protein None
Description This product is a recombinant Human antibody targeted to the SARS-CoV RBD domain of the Spike protein. It was produced in Nicotiana benthamiana plants via Agrobacterium tumefaciens mediated infiltration.
Target name SARS-CoV/-2 Receptor Binding Domain (RBD)
Target sequence N/A
Verified applications Western blot
ELISA
Concentration 1.0 mg/ml
Form Liquid
Colour Clear to light yellow-brown
Preparation Ready to use
Storage Short term (up to one week): 2 – 8 °C
Long term: Aliquot and store at – 20 °C
Store immediately. Aliquot and avoid multiple freeze thaw cycles.
Storage buffer 0.1  M Phosphate Buffered Saline, pH 7.4
Preservative: None
Purification notes This product was purified using Protein A affinity chromatography.
Purity ≥ 85 % as determined by SDS-PAGE
General notes If for any reason the product does not perform as specified, please contact our scientific support team for assistance by emailing sales@capebiologix.com.

PtX™ | Plant-Based Expression

The biotechnology behind the development and manufacture of this product, transient plant-based expression, effectively turns Nicotiana benthamiana plants into single use, biodegradable bioreactors. Transforming Agrobacterium tumefaciens cells with our proprietary plant expression vectors, allows rapid production of a wide variety of foreign proteins. We then harvest the plants and extract the protein through various stages of filtration, centrifugation, and purification – providing our final product in the end.

Visit our Technology page to learn more.

Important!

  • For Research Use Only.
  • Not for diagnostic or therapeutic use.
  • Not for resale without express authorization.
  • Trademark.

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