Human Anti-hCG

Recombinant human monoclonal antibody against native Human Chorionic Gonadotropin. Produced in Nicotiana benthamiana plants for use in ELISA application.

100 µg      |     Catalogue Number: CBT_A0017

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Human Chorionic Gonadotrophin (hCG) is a glycoprotein hormone that is primarily produced by the placenta during pregnancy. It is composed of an alpha and beta subunit, where the alpha subunit shares homology to other glycoprotein hormones such as follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH). The beta subunit, on the other hand, is unique to hCG and is responsible for its biological activity, that includes promoting development and maintenance of the corpus luteum, which produces progesterone to support pregnancy. Additionally, hCG is commonly used as a marker for pregnancy and is also used in the treatment of certain medical conditions such as infertility and testicular cancer. The high specificity of our human anti-chorionic gonadotrophin antibody to the beta subunit of native form hCG ensures accurate and reliable results. It is suitable for ELISA application and designed to provide researchers with a powerful tool for studying the biology and function of hCG in fertility health and disease.

Additional information

Available Unit Size

0.1mg, 1mg, 10mg, 100mg, 200mg

Key Benefits

This product is a recombinant monoclonal antibody that offers several benefits including the following:

  • Able to detect hCG protein in its native conformation.
  • Batch-to-batch consistency.
  • No animals or animal products are used in the development of this protein.
  • BSA and Azide free.

For more information on plant-made, recombinant monoclonal antibodies click here.

Datasheet

Product Name PtX™ Human Anti-Human Chorionic Gonadotropin Recombinant Antibody
Catalogue Number CBT_A0017
Expression Host Nicotiana benthamiana plants
Clonality Monoclonal, recombinant
Species and Isotype Human IgG1
Tag None
Reporter Protein None
Description This product is a full-length Human IgG1 antibody specific to the Native Human hCG protein. It was produced recombinantly in Nicotiana benthamiana plants via Agrobacterium tumefaciens mediated infiltration.
Target name Native hCG protein
Verified Applications ELISA
Recommended Dilutions ELISA (1: 4 000 – 1: 256 000)
Concentration 1.0 mg/ml
Form Liquid
Colour Clear
Preparation Ready to use
Storage Short-term (up to one week): 2 – 8 °C
Long term: Aliquot and store at – 20 °C
Store immediately. Aliquot and avoid multiple freeze-thaw cycles.
Storage buffer 0.1  M Phosphate Buffered Saline, pH 7.4
Preservative: None
Purification notes This product was purified using Protein A affinity chromatography.
Purity ≥ 95% as determined by SDS-PAGE
General notes If for any reason the product does not perform as specified, please contact our scientific support team for assistance by emailing sales@capebiologix.com.

Images

Figure 1. ELISA Dose Response curve using PtX™ Human Anti-hCG to detect coated Human hCG at 1 ng/µl and increasing concentrations of antibody. Experiments were performed in triplicate, with error bars representing standard deviation (SD).

PtX™ | Plant-Based Expression

The biotechnology behind the development and manufacture of this product, transient plant-based expression, effectively turns Nicotiana benthamiana plants into single-use, biodegradable bioreactors. Infiltrating this plant species with Agrobacterium tumefaciens cells, transformed with our proprietary plant expression vectors, allows rapid production of a wide variety of recombinant proteins. Plants are harvested and proteins extracted by various stages of filtration, clarification, purification, and polishing – resulting in a highly functional final product.

Visit our Technology page to learn more.

Important!

  • For Research Use Only.
  • Not for diagnostic or therapeutic use.
  • Not for resale without express authorization.
  • Trademark.

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