Human Anti-IL-2 (1F90) (HRP)

This product is a full-length Human IgG1 recombinant antibody specific to Interleukin 2, fused at the genetic level to HRP reporter enzyme. It was produced in Nicotiana benthamiana plants via Agrobacterium tumefaciens-mediated infiltration.

100 µg      |     Catalogue Number: CBT_A0060

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Interleukin-2 (IL-2) is a cytokine that plays a critical role in regulating the immune system. It is primarily produced by activated T cells and acts as a key mediator of immune responses. IL-2 functions by binding to specific receptors on various immune cells, including T cells, B cells, and natural killer (NK) cells, which triggers a cascade of signaling events that promote the activation, proliferation, and differentiation of these immune cells. Additionally, IL-2 promotes the development and maintenance of regulatory T cells (Tregs), which play a crucial role in immune tolerance and preventing autoimmune responses. IL-2 also supports the differentiation of NK cells, boosting their cytotoxic activity against target cells. In cancer immunotherapy, IL-2 has been used to stimulate the immune system and enhance the antitumor activity of T cells and NK cells. Furthermore, IL-2 has been studied to understand its impact on the development of immunological memory and as a potential adjuvant in vaccine design.

The stringent quality control processes behind our PtX™ Human anti-IL-2 (HRP) antibody ensures optimal performance and reproducibility. Its application potential and reliable performance make it an invaluable tool for scientists, clinicians, and researchers dedicated to advancing immunotherapy, immune regulation, and the understanding of immune-related diseases.

Additional information

Available Unit Size

0.1mg, 1mg, 10mg, 100mg, 200mg

Key Benefits

This product is a recombinant monoclonal antibody that offers several benefits including the following:

  • Enhanced signal intensity and sensitivity
  • Reduced background noise
  • Compatibility with multiple species and antibody isotypes
  • Minimized steric hindrance
  • Batch-to-batch consistency.
  • No animals or animal products are used in the development of this protein.
  • BSA and Azide free.

For more information on plant-made, recombinant monoclonal antibodies click here. 

Datasheet

Product Name PtX™ Human Anti-Interleukin-2 (1F90) (HRP) Recombinant Antibody
Catalogue Number CBT_A0060
Expression Host Nicotiana benthamiana plants
Clonality Monoclonal, recombinant
Species and Isotype Human IgG1
Tag None
Reporter Protein Horseradish Peroxidase (HRP)
Description This product is a full-length Human IgG1 recombinant antibody specific to Interleukin 2 (IL-2), fused at the genetic level to the reporter enzyme HRP. It was produced in Nicotiana benthamiana plants via Agrobacterium tumefaciens-mediated infiltration.
Target Name Interleukin 2 (IL-2)
Verified Applications ELISA, Western blot
Dilution Range ELISA (1: 1 000 – 1: 20 000)

Western blot (1: 1 000 – 1: 3 000)
Tested Species Reactivity     Human
Concentration                   1 mg/ml
Form Liquid
Colour Clear with a faint red tinge
Preparation Ready to use
Storage Short term (up to one week): 2 – 8 °C

Long term: Aliquot and store at – 20 °C

Store immediately. Aliquot and avoid multiple freeze thaw cycles.
Storage Buffer 0.1M Phosphate Buffered Saline, pH 7.4

Preservative: 50% Glycerol
Purification Notes This product was purified using Protein A- affinity chromatography.
Purity 95 % as determined by SDS-PAGE
General Notes If for any reason the product does not perform as specified, please contact our scientific support team for assistance by emailing techsupport@capebiologix.com.

For Research Use only, unless otherwise indicated.

Images

Figure 1. ELISA Dose Response curve: PtX™ Human Anti-IL-2 (HRP) Antibody from 0.0006 – 50 ng/uL to detect 100 ng Interleukin 2 protein. Experiments were performed in triplicate, with error bars representing standard deviation (SD).

Figure 2. Western blot showing decreasing amounts of Interleukin 2 (IL-2) 16.9 kDa (migrates as 2 bands at ~18.4 kDa and 16.6 kDa due to glycosylation) detected with PtX™ Human Anti-IL-2 (HRP) Antibody at 1: 1 000.

PtX™ | Plant-Based Expression

The biotechnology behind the development and manufacture of this product, transient plant-based expression, effectively turns Nicotiana benthamiana plants into single-use, biodegradable bioreactors. Infiltrating this plant species with Agrobacterium tumefaciens cells, transformed with our proprietary plant expression vectors, allows rapid production of a wide variety of recombinant proteins. Plants are harvested and proteins extracted by various stages of filtration, clarification, purification, and polishing – resulting in a highly functional final product.

Visit our Technology page to learn more.

Important!

  • For Research Use Only.
  • Not for diagnostic or therapeutic use.
  • Not for resale without express authorization.
  • Trademark.

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